content moisture traps

Moisture Control Reagents

We set the standard in solvent drying agents and moisture control solutions for oligonucleotide synthesis. Traditionally, molecular sieves have been the preferred method to achieve and maintain low moisture levels in solvents. However, these have several well-known issues, including inconsistent activation, variable performance, limited objective quality control measures, and friction between molecular sieves leading to the generation a fine dust.

Our EZ Dry ULTRA moisture traps revolutionize solvent drying by packaging pre-dried molecular sieves in convenient permeable sachets, allowing moisture to be easily adsorbed from the surrounding solvent while preventing dust from entering the solution.

Setting the Standard in Solvent Drying and Moisture Control


Low moisture levels are essential for reliable oligonucleotide synthesis. Traditional molecular sieves are effective but require time-consuming preparation and quality control. emp Biotech’s EZ Dry ULTRA moisture traps contain pre-dried molecular sieves in permeable sachets, providing a fast, convenient solution for drying solvents in volumes from 100 mL to 20 L.

Revolutionize solvent drying by packaging pre-dried molecular sieves in convenient permeable sachets.

Designed for efficient phosphoramidite coupling across diverse synthesis platforms.

EZ Dry ULTRA performance

EZ Dry ULTRA: standard water content*

* Representative internal performance data

EZ Dry ULTRA: elevated water content*

Core technical characteristics

Passive moisture control

Diffusion-driven, in-bottle moisture trap for long-term reduction of water content, without active gas purging or the need for external power or system modifications.

Low water content maintenance

Maintains water levels at or below 30 ppm in solvents and solvent mixtures during routine storage and handling under defined conditions.

Extended residence time

Designed for long term use, enabling continuous maintenance of low water content without frequent replacement.

Moisture reduction capability

Reduces elevated water content following accidental exposure or handling events with an appropriate trap-to-volume ratio and operating conditions.

Scalable formats

Available in multiple sizes designed to fit a wide range of common laboratory and process solvent volumes – from 100 ml to 20 l – enabling consistent application across scales.

EZ Dry ULTRA moisture traps are manufactured under low humidity conditions and inert atmosphere
for highly regulated environments. All materials are selected and qualified for chemically demanding applications, and comply with 21 CFR 177.1520 (documentation available upon request). EZ Dry ULTRA moisture traps are designed for critical workflows where solvent water content must be maintained at or below 20 ppm.